See the definition of issue in the KJV Dictionary

(1) (moledheth, tse'etsa'im; sperma, "seed"): Offspring, descendants (Ge 48:6; Isa 22:24; Mt 22:25 the King James Version).

(2) (zirmah; yatsa' (verb); rhusis): A gushing of fluid (semen, Eze 23:20; water, Eze 47:8; blood, Lu 8:43). See next article.

See also the McClintock and Strong Biblical Cyclopedia.

Bible Verses by Topic Nave's Bible Concordance McClintock and Strong Biblical Cyclopedia Online Bible KJV Dictionary

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